André Beauchemin

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André Beauchemin
Full Professor and Vice-Dean, Graduate Studies and Entrepreneurship

B.Sc. Université Laval (1996)
Ph.D. Université de Montréal (2001)

Room: DRO 306
Office: 613-562-5800 ext. 2245
Work E-mail: andre.beauchemin@uOttawa.ca

Biography

Dr. Beauchemin's research program focuses on the development of new synthetic methods and their application in total synthesis of natural products and privileged structures in bioactive molecules. Special focus is put on the development of efficient syntheses of nitrogen-containing molecules since over 90% of the drugs on the market possess at least one nitrogen atom in their structure and approximately one reaction out of six performed in the pharmaceutical industry involves the formation of a carbon-nitrogen bond.

Selected publications

  • Derasp, J. S.; Beauchemin, A. M. Rhodium-Catalyzed Synthesis of Amides from Functionalized Blocked Isocyanates. ACS Catal. 2019, 9, 8104-8109.
  • Vincent-Rocan, J.-F.; Ivanovich, R. A.; Clavette, C.; Leckett, K.; Bejjiani, J.; Beauchemin, A. M. Cascade Reactions of Nitrogen-Substituted Isocyanates: A New Tool in Heterocyclic Chemistry” Chem. Sci. 2016, 7, 315-328.
  • Clavette, C.; Gan, W.; Bongers, A.; Markiewicz, T.; Toderian, A.; Gorelsky, S. I.; Beauchemin, A. M. A Tunable Route for the Synthesis of Azomethine Imines and β-Aminocarbonyl Compounds from Alkenes J. Am. Chem. Soc. 2012, 134, 16111-16114.
  • MacDonald, M. J.; Schipper, D. J.; Ng, P. J.; Moran, J.; Beauchemin, A.M. A Catalytic Tethering Strategy: Simple Aldehydes Catalyze Intermolecular Alkene Hydroaminations. J. Am. Chem. Soc. 2011, 133, 20100-20103.
  • Moran, J., Gorelsky, S.I., Dimitrijevic, E., Lebrun, M.-E., Bédard, A.-C., Séguin, C., Beauchemin, A.M. Intermolecular cope-type hydroamination of alkenes and alkynes using hydroxylamines. J. Am. Chem. Soc. 2008, 130, 17893-17906.

Fields of Interest

  • Organic and Biological Chemistry
  • Synthetic organic chemistry
  • Total synthesis
  • Catalysis
  • Amination
  • Heterocyclic chemistry
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