Office: (613) 562-5800 ext. 6964
Work E-mail: tcossa@uOttawa.ca
Dr. T.-Cossa's research is dedicated to the development of novel techniques to manipulate and characterize single molecules using nanoscale devices, and to the translation of discoveries into new tools for the health and biological sciences. The exploration of new approaches to probe the dynamics and the interactions of molecules within nanofluidic environments: (i) represents an important and largely unexplored regime in which interesting new physics can dominate, and (ii) enables quantitative measurements, with exceptional sensitivity, on the structure and behavior of biological molecules.
- Tabard-Cossa, V., Wiggin, M., Trivedi, D., Jetha, N.N., Dwyer, J.R., Marziali, A. Single-molecule bonds characterized by solid-state nanopore force spectroscopy. ACS Nano 3(10), 3009-2014, 2009
- Branton, D., Deamer, W.D., Marziali, A., Tabard-Cossa, V., et al. The potential and challenges of nanopores sequencing. Nature Biotechnology 26, 1146-1153, 2008
- Wiggin, M., Tropini, C., Tabard-Cossa, V., Jetha, N.N., Marziali, A. Nonexponential kinetics of DNA escape from alpha-hemolysin nanopores. Biophysical Journal 95, 5317-5323, 2008
- Tabard-Cossa, V., Trivedi, D., Wiggin, M., Jetha, N., Marziali, A. Noise analysis and reduction in solid-state nanopores. Nanotechnology 18, 305505, 2007